Overview    |   Hematopoietic, Bone Marrow, Cord Blood    |   Mesenchymal    |   Cardiac    |   Neural    |   Epithelial    |   Pluripotential    |   Tissue Engineering    |   Genomics, Epigenetics, Noncoding RNAs    |   Regeneration    |   Cancer    |   Imaging   |   Germ Line Stem Cell

Stem cells and regeneration

regeneratoinSome human tissues can undergo limited repair after injury, for example during wound healing in skin, and the liver can regenerate whole lobes. However, in general, the regeneration capacity of mammals is very limited compared with vertebrates such as fish and salamanders that can re-grow entire appendages. We would like to know how this extensive regeneration occurs and whether the principles can be applied to humans to make injury repair more efficient. After amputation of a fin, cells in the stump proliferate and give rise to a population of undifferentiated stem cells called the blastema. Scientists are studying the properties of blastema cells and how they differentiate in an orderly way to form a complete appendage of the same size and shape as the one that was lost.

Nenad Bursac, Ph.D.
Assistant Professor,Department of Biomedical Engineering
3000 Science Drive, Hudson Hall - Engineering, Room 136
Duke University
Durham, NC 27708
Phone: 919-660-5510
E-mail: nbrusac@duke.edu
Website

Anna Mae Diehl, M.D.
Professor
Department of Medicine and Chief, Division of Gastroenterology
Box 3256, DUMC, Durham, NC  27710
Phone: 919-684-4173
E-mail: annamae.diehl@duke.edu
Website

Cagla Eroglu, Ph.D.
Assistant Professor
Department of Cell Biology
Box 3709, DUMC, Durham, NC  27710
Phone: 919-684-3605
E-mail:c.eroglu@cellbio.duke.edu
Website

Don Fox, Ph.D.
Pharmacology & Cancer Biology
Duke Box 3813
C318 LSRC
Durham, NC 27710
Phone: 919 613-8756(tel)
E-mail: don.fox@duke.edu
Website

Matthew J. Hilton, PhD
Associate Professor of Orthopaedic Surgery
Duke University School of Medicine
Duke Musculoskeletal Research Center
Cellular, Developmental, and Genome Laboratories
450 Research Drive, LSRC B321C
DUMC Box 91009
Durham, NC 27710
Lab Phone: (919) 613-9753
Office Phone: (919) 613-9761
Email: matthew.hilton@dm.duke.edu
Website

Chay Kuo, M.D., Ph.D.
Assistant Professor
Department of Cell Biology
Box 3709, DUMC
Phone: 684-4612
E-mail: c.kuo@cellbio.duke.edu
Website
Joanne Kurtzberg, M.D.
Department of Pediatrics
Bone Marrow Transplant Program
Box 3350, DUMC, Durham, NC  27710
Phone: 919-668-1100
E-mail: kurtz001@mc.duke.edu
Website

Chuan-Yuan Li
Department of Dermatology
Box 3135 DUMC
C303A LSRC
Durham, NC 27710
Phone: 919 613 8754
E-mail: chuan.li@duke.edu
Website

Jennifer Moss PhD
Assistant Professor of Medicine
Endocrine Division and DMPI
Box 104775 DUMC, Durham, NC, 27710
Phone:  919-479-2379
E-mail: jennifer.b.moss@dm.duke.edu
Website

Larry Moss
Associate Professor of Medicine
Endocrine Division and DMPI
Box 104775 DUMC, Durham, NC, 27710
Phone: 919-479-2310
E-mail: larry.moss@dm.duke.edu
Website

Ken Poss, Ph.D.
Assistant Professor
Department of Cell Biology
Box 3709, DUMC, Durham, NC  27710
Phone: 919-681-8457
E-mail: Kenneth.poss@duke.edu
Website

Dong Yan
Department of Molecular Genetics and Microbiology
Duke University Medical Center
Durham, NC 27710
E-mail: dong.yan@dm.duke.edu